Open () failed (24 too many open files

I have a lot of below error in error.log.
Open /home/user/… failed (24 too many open files.
So i search in google and config below files.
Limits.conf , sysctl.conf nginx.conf for adjust rlimit nofile.
I set open file limit to 999999 and fs.max to 2000000.

When i am geting error i used command ( lsof | wc -l ) for see total
file that it show 16000.
I use command ( cd /proc/nginx pid/limits ) it show max open file
Now i am geting above error yet.
So what is problem?

Posted at Nginx Forum:,267827,267827#msg-267827

anybody don’t know about that ?

Posted at Nginx Forum:,267827,267861#msg-267861