Error unlink() nginx 1.2.6

the error.log file I get the error: 12/29/2012 12:40:39 [crit] 16489 #
0:
unlink () “/ var/cache/cafe2/2/9e/5d7f005ef7a1b948e522a3b8ed5959e2”
failed
(2: No such file or directory)
the folder has permissions 777. how to fix this?

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