Connection failed error

I am getting the below error while i try to get response from API. What
should I do to solve this

c:/ruby/lib/ruby/1.8/net/http.rb:564:in initialize': A connection attempt failed because the connected party did not properly respond after a period of time, or established connection failed because connected host has failed to respond. - connect(2) (Errno::ETIMEDOUT) from c:/ruby/lib/ruby/1.8/net/http.rb:564:inopen’
from c:/ruby/lib/ruby/1.8/net/http.rb:564:in connect' from c:/ruby/lib/ruby/1.8/timeout.rb:48:intimeout’
from c:/ruby/lib/ruby/1.8/timeout.rb:76:in timeout' from c:/ruby/lib/ruby/1.8/net/http.rb:564:inconnect’
from c:/ruby/lib/ruby/1.8/net/http.rb:557:in do_start' from c:/ruby/lib/ruby/1.8/net/http.rb:546:instart’
from c:/ruby/lib/ruby/1.8/open-uri.rb:243:in open_http' from c:/ruby/lib/ruby/1.8/open-uri.rb:617:inbuffer_open’
from c:/ruby/lib/ruby/1.8/open-uri.rb:164:in open_loop' from c:/ruby/lib/ruby/1.8/open-uri.rb:162:incatch’
from c:/ruby/lib/ruby/1.8/open-uri.rb:162:in open_loop' from c:/ruby/lib/ruby/1.8/open-uri.rb:132:inopen_uri’
from c:/ruby/lib/ruby/1.8/open-uri.rb:519:in open' from c:/ruby/lib/ruby/1.8/open-uri.rb:30:inopen’
from wishpot.rb:19:in `create_urlrequest’
from wishpot.rb:50